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pentobarbital will decrease the extent or outcome of cilostazol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will reduce the extent or outcome of ixabepilone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will decrease the extent or impact of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will reduce the level or effect of buprenorphine subdermal implant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Observe clients presently on buprenorphine subdermal implant who have to have recently-initiated treatment method with CYP3A4 inducer for signals and signs or symptoms of withdrawal.

Watch Intently (one)pentobarbital will minimize the extent or impact of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

benzhydrocodone/acetaminophen and pentobarbital both enhance sedation. Avoid or Use Alternate Drug. Restrict use to patients for whom alternate treatment method choices are insufficient

pentobarbital improves effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Caution/Observe. Coadministration of ifosfamide with CYP2B6 inducers may possibly improve metabolism of ifosfamide to its metabolite. Keep track of for elevated effects/toxicities if coupled with CYP2B6 inducers.

Observe Intently (1)pentobarbital will lower the level or result of buprenorphine subdermal implant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. read more Monitor patients presently on buprenorphine subdermal implant who demand freshly-initiated treatment with CYP3A4 inducer for symptoms and symptoms of withdrawal. In case the dose from the concomitant CYP3A4 inducer can not be lowered or discontinued, implant removing could possibly be needed as well as the affected person should then be addressed using a buprenorphine dosage sort that allows dose adjustments.

pentobarbital will lessen the extent or impact of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.

pentobarbital will lower the extent or result of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will lower the extent or impact of temsirolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will reduce the level or outcome of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.

pentobarbital will lower the level or impact of ziprasidone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.